1. Study Overview
Living to 100 is becoming more common, but researchers wanted to know whether routine blood tests taken decades earlier could predict exceptional longevity.
As they wrote, “Participants were followed in Swedish register data for up to 35 years.”
The study looked at common markers such as glucose, cholesterol, kidney and liver function, and inflammation.
2. Who Was Studied
Using the AMORIS cohort, researchers examined 44,636 people tested between 1985–1996.
Of these, 1,224 reached 100. The authors noted that “half of the participants were followed for more than 10 years,” strengthening the study’s patterns.
3. Key Findings
Low cholesterol reduced the odds of reaching 100: “Low cholesterol was associated with a reduced likelihood of reaching the age of 100,” while “having high cholesterol neither increases nor decreases the probability.”
Extremely high glucose, uric acid, and several liver or kidney markers also predicted lower odds.
4. What It Means
Overall, extreme highs—or lows—across many markers signaled reduced longevity.
Moderate, balanced ranges appeared most favorable.
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